Since the establishment of the Biomedical Discipline by the Hong Kong Institution of Engineers (HKIE) in 2004, the status of biomedical engineers in Hong Kong has been recognised and raised, leading to the further enhancement of the professionalism. As a multi-disciplinary professional, biomedical engineering penetrates various aspects, e.g. orthopaedics, prosthesis, bioinformatics, biomechanics, biomaterials, rehabilitation, and sterilisation. The biomedical engineering professional has been provided with increasing attention in Hong Kong through the continuous promotion of the high level engineering practice and integrity, the provision of new initiatives in research and development (R&D), as well as the active participation in supporting the medical device listing and future mandatory regulations, making Hong Kong and the BME2010 Biomedical Engineering International Conference and Pre-Conference Workshop, Hong Kong, the most timely platform for information exchange. The BME conference series has been a biennial converging point of biomedical professionals of different nationalities, disciplines and research foci since 1992. BME2010 Hong Kong composes of 2-day scientific presentation and workshop, 1-day pre-conference workshop plus 1-day technical visit, serves as a platform for the biomedical engineers, researchers, regulators, industrialists and healthcare professionals to exchange the latest information and achievements. Presentation topics cover from laboratory research to clinical application, facilitating the idea exchange on the new advancement of R&D and industry update in a wide spectrum and allowing further promotion of the professional development in the field.